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The retinoblastoma gene product interacts with maintenance human DNA (cytosine-5) methyltransferase and modulates its activity

The mammalian DNA (cytosine-5) methyltransferase (Dnmt1) is involved in the maintenance of methylation patterns in the genome during DNA replication and development. The retinoblastoma gene product, Rb, is a cell cycle regulator protein that represses transcription by recruiting histone deacetylase...

Полное описание

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Библиографические подробности
Главные авторы: Pradhan, Sriharsa, Kim, Gun-Do
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2002
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC125847/
https://ncbi.nlm.nih.gov/pubmed/11847125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.4.779
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