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Hybrid mouse–prokaryotic DNA (cytosine-5) methyltransferases retain the specificity of the parental C-terminal domain

The mouse (cytosine-5) DNA methyltransferase (Dnmt1) consists of a regulatory N-terminal and a catalytic C-terminal domain, which are fused by a stretch of Gly-Lys dipeptide repeats. The C-terminal region contains all of the conserved motifs found in other cytosine-5 DNA methyltransferases including...

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Detalhes bibliográficos
Main Authors: Pradhan, Sriharsa, Roberts, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC305692/
https://ncbi.nlm.nih.gov/pubmed/10790376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.9.2103
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