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Functional analysis of the N- and C-terminus of mammalian G9a histone H3 methyltransferase

Methylation of lysine 9 (K9) in the N-terminus tail of histone H3 (H3) in chromatin is associated with transcriptionally silenced genes and is mediated by histone methyltransferases. Murine G9a is a 1263 amino acid H3-K9 methyltransferase that possesses characteristic SET domain and ANK repeats. In...

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Bibliographic Details
Main Authors: Estève, Pierre-Olivier, Patnaik, Debasis, Chin, Hang Gyeong, Benner, Jack, Teitell, Michael A., Pradhan, Sriharsa
Format: Artigo
Language:Inglês
Published: Oxford University Press 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143580/
https://ncbi.nlm.nih.gov/pubmed/15939934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki635
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