Direct interaction between DNMT1and G9a coordinates DNA and histone methylation during replication

Chromatin methylation is necessary for stable repression of gene expression during mammalian development. During cell division, DNMT1 maintains the DNA methylation pattern of the newly synthesized daughter strand, while G9a methylates H3K9. Here, DNMT1 is shown to directly bind G9a both in vivo and...

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Autori principali: Estève, Pierre-Olivier, Chin, Hang Gyeong, Smallwood, Andrea, Feehery, George R., Gangisetty, Omkaram, Karpf, Adam R., Carey, Michael F., Pradhan, Sriharsa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2006
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635145/
https://ncbi.nlm.nih.gov/pubmed/17085482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1463706
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