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Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells

Inheritance of epigenetic information encoded by cytosine DNA methylation patterns is crucial for mammalian cell survival, in large part through the activity of the maintenance DNA methyltransferase (DNMT1). Here, we show that SET7, a known histone methyltransferase, is involved in the regulation of...

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Hlavní autoři: Estève, Pierre-Olivier, Chin, Hang Gyeong, Benner, Jack, Feehery, George R., Samaranayake, Mala, Horwitz, Gregory A., Jacobsen, Steven E., Pradhan, Sriharsa
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654809/
https://ncbi.nlm.nih.gov/pubmed/19282482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810362106
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