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Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells

Inheritance of epigenetic information encoded by cytosine DNA methylation patterns is crucial for mammalian cell survival, in large part through the activity of the maintenance DNA methyltransferase (DNMT1). Here, we show that SET7, a known histone methyltransferase, is involved in the regulation of...

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Bibliografiska uppgifter
Huvudupphovsmän: Estève, Pierre-Olivier, Chin, Hang Gyeong, Benner, Jack, Feehery, George R., Samaranayake, Mala, Horwitz, Gregory A., Jacobsen, Steven E., Pradhan, Sriharsa
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2009
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654809/
https://ncbi.nlm.nih.gov/pubmed/19282482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810362106
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