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Functional cooperation between HP1 and DNMT1 mediates gene silencing

Mammalian euchromatic gene silencing results from the combined repressive effects of histone and DNA methyltransferases. Little is known of the mechanism by which these enzymes cooperate to induce silencing. Here we show that mammalian HP1 family members mediate communication between histone and DNA...

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Detalhes bibliográficos
Main Authors: Smallwood, Andrea, Estève, Pierre-Olivier, Pradhan, Sriharsa, Carey, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865489/
https://ncbi.nlm.nih.gov/pubmed/17470536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1536807
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