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Functional cooperation between HP1 and DNMT1 mediates gene silencing
Mammalian euchromatic gene silencing results from the combined repressive effects of histone and DNA methyltransferases. Little is known of the mechanism by which these enzymes cooperate to induce silencing. Here we show that mammalian HP1 family members mediate communication between histone and DNA...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1865489/ https://ncbi.nlm.nih.gov/pubmed/17470536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1536807 |
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