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Engineering the DNA cytosine-5 methyltransferase reaction for sequence-specific labeling of DNA
DNA methyltransferases catalyse the transfer of a methyl group from the ubiquitous cofactor S-adenosyl-L-methionine (AdoMet) onto specific target sites on DNA and play important roles in organisms from bacteria to humans. AdoMet analogs with extended propargylic side chains have been chemically prod...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526304/ https://ncbi.nlm.nih.gov/pubmed/23042683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks914 |
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