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Small RNA-mediated DNA (cytosine-5) methyltransferase 1 inhibition leads to aberrant DNA methylation

Mammalian cells contain copious amounts of RNA including both coding and noncoding RNA (ncRNA). Generally the ncRNAs function to regulate gene expression at the transcriptional and post-transcriptional level. Among ncRNA, the long ncRNA and small ncRNA can affect histone modification, DNA methylatio...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Zhang, Guoqiang, Estève, Pierre-Olivier, Chin, Hang Gyeong, Terragni, Jolyon, Dai, Nan, Corrêa, Ivan R., Pradhan, Sriharsa
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499142/
https://ncbi.nlm.nih.gov/pubmed/25990724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv518
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