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HIV Neutralizing Antibodies Induced by Native-like Envelope Trimers
A challenge for HIV-1 immunogen design is inducing neutralizing antibodies (NAbs) against neutralization-resistant (Tier-2) viruses that dominate human transmissions. We show that a soluble recombinant HIV-1 envelope glycoprotein trimer that adopts a native conformation (BG505 SOSIP.664) induced NAb...
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4498988/ https://ncbi.nlm.nih.gov/pubmed/26089353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aac4223 |
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