HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers

Rabbits and monkeys immunized with HIV type 1 (HIV-1) native-like BG505 SOSIP.664 (BG505s) glycoprotein trimers are known to induce antibodies that can neutralize the autologous tier-2 virus. Here, we assessed the induction of HIV-1 trimer binding and neutralizing antibody (nAb) titres when BG505s t...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Capucci, Silvia, Wee, Edmund G., Schiffner, Torben, LaBranche, Celia C., Borthwick, Nicola, Cupo, Albert, Dodd, Jonathan, Dean, Hansi, Sattentau, Quentin, Montefiori, David, Klasse, Per J., Sanders, Rogier W., Moore, John P., Hanke, Tomáš
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549892/
https://ncbi.nlm.nih.gov/pubmed/28792942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181886
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