HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers

Rabbits and monkeys immunized with HIV type 1 (HIV-1) native-like BG505 SOSIP.664 (BG505s) glycoprotein trimers are known to induce antibodies that can neutralize the autologous tier-2 virus. Here, we assessed the induction of HIV-1 trimer binding and neutralizing antibody (nAb) titres when BG505s t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Capucci, Silvia, Wee, Edmund G., Schiffner, Torben, LaBranche, Celia C., Borthwick, Nicola, Cupo, Albert, Dodd, Jonathan, Dean, Hansi, Sattentau, Quentin, Montefiori, David, Klasse, Per J., Sanders, Rogier W., Moore, John P., Hanke, Tomáš
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549892/
https://ncbi.nlm.nih.gov/pubmed/28792942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181886
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