Renal involvement in lupus is characterized by unique DNA methylation changes in naïve CD4+ T cells

Systemic lupus erythematosus is a multi-system disease characterized by wide-spread DNA methylation changes. To identify epigenetic susceptibility loci for lupus nephritis, genome-wide DNA methylation changes in naïve CD4+ T cells were compared between two sets of lupus patients with and without a h...

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Publicado en:J Autoimmun
Autores principales: Coit, Patrick, Renauer, Paul, Jeffries, Matlock A., Merrill, Joan T., McCune, W. Joseph, Maksimowicz-McKinnon, Kathleen, Sawalha, Amr H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497927/
https://ncbi.nlm.nih.gov/pubmed/26005050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2015.05.003
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