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A longitudinal and transancestral analysis of DNA methylation patterns and disease activity in lupus patients
Epigenetic dysregulation is implicated in the pathogenesis of lupus. We performed a longitudinal analysis to assess changes in DNA methylation in lupus neutrophils over 4 years of follow-up and across disease activity levels using 229 patient samples. We demonstrate that DNA methylation profiles in...
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| Pubblicato in: | JCI Insight |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7710270/ https://ncbi.nlm.nih.gov/pubmed/33108347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.143654 |
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