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Age-associated DNA methylation changes in naive CD4(+) T cells suggest an evolving autoimmune epigenotype in aging T cells
AIM: We sought to define age-associated DNA methylation changes in naive CD4(+) T cells. MATERIALS & METHODS: Naive CD4(+) T cells were collected from 74 healthy individuals (age 19–66 years), and age-related DNA methylation changes were characterized. RESULTS: We identified 11,431 age-associate...
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| Pubblicato in: | Epigenomics |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Future Medicine Ltd
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5549647/ https://ncbi.nlm.nih.gov/pubmed/28322571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi-2016-0143 |
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