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Autoimmunity-associated protein tyrosine phosphatase PEP negatively regulates IFN-α receptor signaling
The protein tyrosine phosphatase PTPN22(C1858T) allelic polymorphism is associated with increased susceptibility for development of systemic lupus erythematosus (SLE) and other autoimmune diseases. PTPN22 (also known as LYP) and its mouse orthologue PEP play important roles in antigen and Toll-like...
שמור ב:
| הוצא לאור ב: | J Exp Med |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The Rockefeller University Press
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4493413/ https://ncbi.nlm.nih.gov/pubmed/26077719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20142130 |
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