Autoimmunity-associated protein tyrosine phosphatase PEP negatively regulates IFN-α receptor signaling

The protein tyrosine phosphatase PTPN22(C1858T) allelic polymorphism is associated with increased susceptibility for development of systemic lupus erythematosus (SLE) and other autoimmune diseases. PTPN22 (also known as LYP) and its mouse orthologue PEP play important roles in antigen and Toll-like...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:J Exp Med
Glavni autori: Holmes, Derek A., Suto, Eric, Lee, Wyne P., Ou, Qinglin, Gong, Qian, Smith, Hamish R.C., Caplazi, Patrick, Chan, Andrew C.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2015
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493413/
https://ncbi.nlm.nih.gov/pubmed/26077719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20142130
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items