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Lymphoid tyrosine phosphatase and autoimmunity: human genetics rediscovers tyrosine phosphatases

A relatively large number of protein tyrosine phosphatases (PTPs) are known to regulate signaling through the T cell receptor (TCR). Recent human genetics studies have shown that several of these PTPs are encoded by major autoimmunity genes. Here, we will focus on the lymphoid tyrosine phosphatase (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Stanford, Stephanie M., Mustelin, Tomas M., Bottini, Nunzio
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881161/
https://ncbi.nlm.nih.gov/pubmed/20204370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00281-010-0201-4
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