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Lymphoid tyrosine phosphatase and autoimmunity: human genetics rediscovers tyrosine phosphatases

A relatively large number of protein tyrosine phosphatases (PTPs) are known to regulate signaling through the T cell receptor (TCR). Recent human genetics studies have shown that several of these PTPs are encoded by major autoimmunity genes. Here, we will focus on the lymphoid tyrosine phosphatase (...

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Bibliographic Details
Main Authors: Stanford, Stephanie M., Mustelin, Tomas M., Bottini, Nunzio
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881161/
https://ncbi.nlm.nih.gov/pubmed/20204370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00281-010-0201-4
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