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Targeting Tyrosine Phosphatases: Time to End the Stigma

Protein tyrosine phosphatases (PTPs) are a family of enzymes essential for numerous cellular processes, and several PTPs have been validated as therapeutic targets for human diseases. Historically, development of drugs targeting PTPs has been highly challenging, leading to stigmatization of these en...

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Bibliografske podrobnosti
izdano v:Trends Pharmacol Sci
Main Authors: Stanford, Stephanie M., Bottini, Nunzio
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494996/
https://ncbi.nlm.nih.gov/pubmed/28412041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2017.03.004
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