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Protein tyrosine phosphatases in systemic sclerosis: potential pathogenic players and therapeutic targets

The pathogenesis of systemic sclerosis depends on a complex interplay between autoimmunity, vasculopathy and fibrosis. Reversible phosphorylation on tyrosine residues in response to growth factors and other stimuli critically regulates each one of these key pathogenic processes. Protein tyrosine kin...

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Detalhes bibliográficos
Publicado no:Curr Rheumatol Rep
Main Authors: Sacchetti, Cristiano, Bottini, Nunzio
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703857/
https://ncbi.nlm.nih.gov/pubmed/28397126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11926-017-0655-7
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