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Drugging the Undruggable: Therapeutic Potential of Targeting Protein Tyrosine Phosphatases

Protein tyrosine phosphatases (PTPs) are essential signaling enzymes that, together with protein tyrosine kinases, regulate tyrosine phosphorylation inside the cell. Proper level of tyrosine phosphorylation is important for a diverse array of cellular processes, such as proliferation, metabolism, mo...

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Vydáno v:Acc Chem Res
Hlavní autor: Zhang, Zhong-Yin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347733/
https://ncbi.nlm.nih.gov/pubmed/27977138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.6b00537
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