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Drugging the Undruggable: Therapeutic Potential of Targeting Protein Tyrosine Phosphatases

Protein tyrosine phosphatases (PTPs) are essential signaling enzymes that, together with protein tyrosine kinases, regulate tyrosine phosphorylation inside the cell. Proper level of tyrosine phosphorylation is important for a diverse array of cellular processes, such as proliferation, metabolism, mo...

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Détails bibliographiques
Publié dans:Acc Chem Res
Auteur principal: Zhang, Zhong-Yin
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347733/
https://ncbi.nlm.nih.gov/pubmed/27977138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.6b00537
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