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Drugging the Undruggable: Therapeutic Potential of Targeting Protein Tyrosine Phosphatases

Protein tyrosine phosphatases (PTPs) are essential signaling enzymes that, together with protein tyrosine kinases, regulate tyrosine phosphorylation inside the cell. Proper level of tyrosine phosphorylation is important for a diverse array of cellular processes, such as proliferation, metabolism, mo...

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Bibliografiska uppgifter
I publikationen:Acc Chem Res
Huvudupphovsman: Zhang, Zhong-Yin
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347733/
https://ncbi.nlm.nih.gov/pubmed/27977138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.6b00537
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