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Drugging the Undruggable: Therapeutic Potential of Targeting Protein Tyrosine Phosphatases
Protein tyrosine phosphatases (PTPs) are essential signaling enzymes that, together with protein tyrosine kinases, regulate tyrosine phosphorylation inside the cell. Proper level of tyrosine phosphorylation is important for a diverse array of cellular processes, such as proliferation, metabolism, mo...
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| Опубликовано в: : | Acc Chem Res |
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| Главный автор: | |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6347733/ https://ncbi.nlm.nih.gov/pubmed/27977138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.6b00537 |
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