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Regulatory Mechanisms and Novel Therapeutic Targeting Strategies for Protein Tyrosine Phosphatases

Appropriate level of protein phosphorylation on tyrosine is essential for cells to react to extracellular stimuli and keep cellular homeostasis. Faulty operation of signal pathways mediated by protein tyrosine phosphorylation causes numerous human diseases, which presents enormous opportunities for...

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Foilsithe in:Chem Rev
Main Authors: Yu, Zhi-Hong, Zhang, Zhong-Yin
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812791/
https://ncbi.nlm.nih.gov/pubmed/28541680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.7b00105
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