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Growth factor identity is encoded by discrete coiled coil rotamers in the EGFR juxtamembrane region
Binding of the growth factor TGF-α to the EGFR extracellular domain is encoded through the formation of a unique anti-parallel coiled coil within the juxtamembrane segment. This new coiled coil is an ‘inside-out’ version of the coiled coil formed in the presence of EGF. A third, intermediary coiled...
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| Gepubliceerd in: | Chem Biol |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4487654/ https://ncbi.nlm.nih.gov/pubmed/26091170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.05.008 |
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