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Discrete Coiled Coil Rotamers Form within the EGFRvIII Juxtamembrane Domain
Mutations in the epidermal growth factor receptor (EGFR) extracellular domain (ECD) are implicated in the development of glioblastoma multiforme (GBM), which is a highly aggressive form of brain cancer. Of particular interest to GBM is the EGFR variant known as EGFRvIII, which is distinguished by an...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7906117/ https://ncbi.nlm.nih.gov/pubmed/32941004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00641 |
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