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Discrete Coiled Coil Rotamers Form within the EGFRvIII Juxtamembrane Domain

Mutations in the epidermal growth factor receptor (EGFR) extracellular domain (ECD) are implicated in the development of glioblastoma multiforme (GBM), which is a highly aggressive form of brain cancer. Of particular interest to GBM is the EGFR variant known as EGFRvIII, which is distinguished by an...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochemistry
Prif Awduron: Mozumdar, Deepto, Doerner, Amy, Zhang, Justin Y., Rafizadeh, Diane N., Schepartz, Alanna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906117/
https://ncbi.nlm.nih.gov/pubmed/32941004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00641
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