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Development of an EGFRvIII specific recombinant antibody

BACKGROUND: EGF receptor variant III (EGFRvIII) is the most common variant of the EGF receptor observed in human tumors. It results from the in frame deletion of exons 2-7 and the generation of a novel glycine residue at the junction of exons 1 and 8. This novel juxtaposition of amino acids within t...

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Detalhes bibliográficos
Main Authors: Gupta, Puja, Han, Shuang-Yin, Holgado-Madruga, Marina, Mitra, Siddhartha S, Li, Gordon, Nitta, Ryan T, Wong, Albert J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959087/
https://ncbi.nlm.nih.gov/pubmed/20925961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-10-72
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