EGFRvIII and c-Met pathway inhibitors synergize against PTEN-null/EGFRvIII(+) glioblastoma xenografts

Receptor tyrosine kinase (RTK) systems, such as hepatocyte growth factor (HGF) and its receptor c-Met, and EGFR, are responsible for the malignant progression of multiple solid tumors. Recent research shows that these RTK systems co-modulate overlapping and dynamically adaptable oncogenic downstream...

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Bibliografiset tiedot
Päätekijät: Lal, Bachchu, Goodwin, Courtney R., Sang, Yingying, Foss, Catherine A., Cornet, Kathrine, Muzamil, Sameena, Pomper, Martin G., Kim, Jin, Laterra, John
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846399/
https://ncbi.nlm.nih.gov/pubmed/19584231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0188
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