טוען...
Influence of Macrocyclization on Allosteric, Juxtamembrane-Derived, Stapled Peptide Inhibitors of the Epidermal Growth Factor Receptor (EGFR)
[Image: see text] The hydrocarbon-stapled peptide E1(S) allosterically inhibits the kinase activity of the epidermal growth factor receptor (EGFR) by blocking a distant but essential protein–protein interaction: a coiled coil formed from the juxtamembrane segment (JM) of each member of the dimeric p...
שמור ב:
| Main Authors: | , |
|---|---|
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American
Chemical Society
2014
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4168776/ https://ncbi.nlm.nih.gov/pubmed/25207804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol502426b |
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