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Epidermal growth factor receptor juxtamembrane region regulates allosteric tyrosine kinase activation
Structural studies of the extracellular and tyrosine kinase domains of the epidermal growth factor receptor (ErbB-1) provide considerable insight into facets of the receptor activation mechanism, but the contributions of other regions of ErbB-1 have not been ascertained. This study demonstrates that...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2148274/ https://ncbi.nlm.nih.gov/pubmed/18042729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703854104 |
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