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Epidermal growth factor receptor juxtamembrane region regulates allosteric tyrosine kinase activation
Structural studies of the extracellular and tyrosine kinase domains of the epidermal growth factor receptor (ErbB-1) provide considerable insight into facets of the receptor activation mechanism, but the contributions of other regions of ErbB-1 have not been ascertained. This study demonstrates that...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2148274/ https://ncbi.nlm.nih.gov/pubmed/18042729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703854104 |
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