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The Intracellular Juxtamembrane Domain of the Epidermal Growth Factor (EGF) Receptor Is Responsible for the Allosteric Regulation of EGF Binding

We have previously shown that the binding of epidermal growth factor (EGF) to its receptor can best be described by a model that involves negative cooperativity in an aggregating system (Macdonald, J. L., and Pike, L. J. (2008) Proc. Natl. Acad. Sci. U. S. A. 105, 112–117). However, despite the fact...

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書誌詳細
主要な著者: Macdonald-Obermann, Jennifer L., Pike, Linda J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679458/
https://ncbi.nlm.nih.gov/pubmed/19336395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.001487
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