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The Intracellular Juxtamembrane Domain of the Epidermal Growth Factor (EGF) Receptor Is Responsible for the Allosteric Regulation of EGF Binding

We have previously shown that the binding of epidermal growth factor (EGF) to its receptor can best be described by a model that involves negative cooperativity in an aggregating system (Macdonald, J. L., and Pike, L. J. (2008) Proc. Natl. Acad. Sci. U. S. A. 105, 112–117). However, despite the fact...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Macdonald-Obermann, Jennifer L., Pike, Linda J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679458/
https://ncbi.nlm.nih.gov/pubmed/19336395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.001487
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