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Epidermal growth factor receptors containing a single tyrosine in their C-terminal tail bind different effector molecules and are signaling-competent

The EGF receptor is a classic receptor tyrosine kinase. It contains nine tyrosines in its C-terminal tail, many of which are phosphorylated and bind proteins containing SH2 or phosphotyrosine-binding (PTB) domains. To determine how many and which tyrosines are required to enable EGF receptor-mediate...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Gill, Kamaldeep, Macdonald-Obermann, Jennifer L., Pike, Linda J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733609/
https://ncbi.nlm.nih.gov/pubmed/29074618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.802553
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