Epidermal growth factor receptors containing a single tyrosine in their C-terminal tail bind different effector molecules and are signaling-competent

Lignende værker

• Allosteric regulation of epidermal growth factor (EGF) receptor ligand binding by tyrosine kinase inhibitors
  af: Macdonald-Obermann, Jennifer L., et al.
  Udgivet: (2018)
• Asp-960/Glu-961 Controls the Movement of the C-terminal Tail of the Epidermal Growth Factor Receptor to Regulate Asymmetric Dimer Formation
  af: Yang, Katherine S., et al.
  Udgivet: (2010)
• The Intracellular Juxtamembrane Domain of the Epidermal Growth Factor (EGF) Receptor Is Responsible for the Allosteric Regulation of EGF Binding
  af: Macdonald-Obermann, Jennifer L., et al.
  Udgivet: (2009)
• The Membrane-proximal Intracellular Domain of the Epidermal Growth Factor Receptor Underlies Negative Cooperativity in Ligand Binding
  af: Adak, Sangeeta, et al.
  Udgivet: (2011)
• Different Epidermal Growth Factor (EGF) Receptor Ligands Show Distinct Kinetics and Biased or Partial Agonism for Homodimer and Heterodimer Formation
  af: Macdonald-Obermann, Jennifer L., et al.
  Udgivet: (2014)