A Potential Peptide Therapeutic Derived from the Juxtamembrane Domain of the Epidermal Growth Factor Receptor

The epidermal growth factor receptor (EGFR) is involved in many cancers and EGFR has been heavily pursued as a drug target. Drugs targeting EGFR have shown promising clinical results for several cancer types. However, resistance to EGFR inhibitors often occurs, such as with KRAS mutant cancers, ther...

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Bibliografski detalji
Glavni autori: Boran, Aislyn D. W., Seco, Joseph, Jayaraman, Vinodh, Jayaraman, Gomathi, Zhao, Shan, Reddy, Sushmitha, Chen, Yibang, Iyengar, Ravi
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499488/
https://ncbi.nlm.nih.gov/pubmed/23166750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049702
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