A Potential Peptide Therapeutic Derived from the Juxtamembrane Domain of the Epidermal Growth Factor Receptor

The epidermal growth factor receptor (EGFR) is involved in many cancers and EGFR has been heavily pursued as a drug target. Drugs targeting EGFR have shown promising clinical results for several cancer types. However, resistance to EGFR inhibitors often occurs, such as with KRAS mutant cancers, ther...

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Bibliographic Details
Main Authors: Boran, Aislyn D. W., Seco, Joseph, Jayaraman, Vinodh, Jayaraman, Gomathi, Zhao, Shan, Reddy, Sushmitha, Chen, Yibang, Iyengar, Ravi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499488/
https://ncbi.nlm.nih.gov/pubmed/23166750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049702
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