A Potential Peptide Therapeutic Derived from the Juxtamembrane Domain of the Epidermal Growth Factor Receptor

The epidermal growth factor receptor (EGFR) is involved in many cancers and EGFR has been heavily pursued as a drug target. Drugs targeting EGFR have shown promising clinical results for several cancer types. However, resistance to EGFR inhibitors often occurs, such as with KRAS mutant cancers, ther...

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Bibliografische gegevens
Hoofdauteurs: Boran, Aislyn D. W., Seco, Joseph, Jayaraman, Vinodh, Jayaraman, Gomathi, Zhao, Shan, Reddy, Sushmitha, Chen, Yibang, Iyengar, Ravi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499488/
https://ncbi.nlm.nih.gov/pubmed/23166750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049702
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