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A Potential Peptide Therapeutic Derived from the Juxtamembrane Domain of the Epidermal Growth Factor Receptor

The epidermal growth factor receptor (EGFR) is involved in many cancers and EGFR has been heavily pursued as a drug target. Drugs targeting EGFR have shown promising clinical results for several cancer types. However, resistance to EGFR inhibitors often occurs, such as with KRAS mutant cancers, ther...

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書誌詳細
主要な著者: Boran, Aislyn D. W., Seco, Joseph, Jayaraman, Vinodh, Jayaraman, Gomathi, Zhao, Shan, Reddy, Sushmitha, Chen, Yibang, Iyengar, Ravi
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499488/
https://ncbi.nlm.nih.gov/pubmed/23166750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049702
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