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Genomic signatures defining responsiveness to allopurinol and combination therapy for lung cancer identified by systems therapeutics analyses

The ability to predict responsiveness to drugs in individual patients is limited. We hypothesized that integrating molecular information from databases would yield predictions that could be experimentally tested to develop transcriptomic signatures for specific drugs. We analyzed lung adenocarcinoma...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Tavassoly, Iman, Hu, Yuan, Zhao, Shan, Mariottini, Chiara, Boran, Aislyn, Chen, Yibang, Li, Lisa, Tolentino, Rosa E., Jayaraman, Gomathi, Goldfarb, Joseph, Gallo, James, Iyengar, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670022/
https://ncbi.nlm.nih.gov/pubmed/31116490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12521
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