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Genomic signatures defining responsiveness to allopurinol and combination therapy for lung cancer identified by systems therapeutics analyses

The ability to predict responsiveness to drugs in individual patients is limited. We hypothesized that integrating molecular information from databases would yield predictions that could be experimentally tested to develop transcriptomic signatures for specific drugs. We analyzed lung adenocarcinoma...

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Détails bibliographiques
Publié dans:Mol Oncol
Auteurs principaux: Tavassoly, Iman, Hu, Yuan, Zhao, Shan, Mariottini, Chiara, Boran, Aislyn, Chen, Yibang, Li, Lisa, Tolentino, Rosa E., Jayaraman, Gomathi, Goldfarb, Joseph, Gallo, James, Iyengar, Ravi
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670022/
https://ncbi.nlm.nih.gov/pubmed/31116490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12521
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