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Mechanism of allosteric coupling into and through the plasma membrane by EGFR

EGFR interacts through its extracellular domain (ECD) with seven different growth factors. These factors induce different structures within the cytoplasmic juxtamembrane segment (JM) of the dimeric receptor and propagate different growth factor-dependent signals to the cell interior. How this proces...

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Bibliografske podrobnosti
izdano v:Cell Chem Biol
Main Authors: Sinclair, Julie K.L., Walker, Allison S., Doerner, Amy E., Schepartz, Alanna
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6054568/
https://ncbi.nlm.nih.gov/pubmed/29731426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.04.005
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