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Mechanism of allosteric coupling into and through the plasma membrane by EGFR
EGFR interacts through its extracellular domain (ECD) with seven different growth factors. These factors induce different structures within the cytoplasmic juxtamembrane segment (JM) of the dimeric receptor and propagate different growth factor-dependent signals to the cell interior. How this proces...
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| Publicado en: | Cell Chem Biol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6054568/ https://ncbi.nlm.nih.gov/pubmed/29731426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.04.005 |
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