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Active Site and Remote Contributions to Catalysis in Methylthioadenosine Nucleosidases
5′-Methylthioadenosine/S-adenosyl-L-homocysteine nucleosidases (MTANs) catalyze the hydrolysis of 5′-methylthioadenosine to adenine and 5-methylthioribose. The amino acid sequences of the MTANs from Vibrio cholerae (VcMTAN) and Escherichia coli (EcMTAN) are 60% identical and 75% similar. Protein str...
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| Publicado en: | Biochemistry |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485437/ https://ncbi.nlm.nih.gov/pubmed/25806409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501487w |
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