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Catalytic Site Cooperativity in Dimeric Methylthioadenosine Nucleosidase

[Image: see text] 5′-Methylthioadenosine/S-adenosylhomocysteine nucleosidases (MTANs) are bacterial enzymes that catalyze hydrolysis of the N-ribosidic bonds of 5′-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) to form adenine and 5-thioribosyl groups. MTANs are involved in AI-1 and AI-2...

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Bibliographic Details
Main Authors: Wang, Shanzhi, Thomas, Keisha, Schramm, Vern L.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977580/
https://ncbi.nlm.nih.gov/pubmed/24502544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401589n
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