Transition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimics

Míreanna Comhchosúla

• Design and Synthesis of Potent “Sulfur-free” Transition State Analogue Inhibitors of 5′-Methylthioadenosine Nucleosidase and 5′-Methylthioadenosine Phosphorylase
  le: Longshaw, Alistair I., et al.
  Foilsithe: (2010)
• A complex of methylthioadenosine/S-adenosylhomocysteine nucleosidase, transition state analogue and nucleophilic water identified by mass spectrometry
  le: Wang, Shanzhi, et al.
  Foilsithe: (2012)
• Transition State Structure of Neisseria meningitides 5′-Methylthioadenosine/S-adenosylhomocysteine Nucleosidase
  le: Singh, Vipender, et al.
  Foilsithe: (2007)
• Transition state analogues of 5′-methylthioadenosine nucleosidase disrupt quorum sensing
  le: Gutierrez, Jemy A., et al.
  Foilsithe: (2009)
• Selective Inhibitors of Helicobacter pylori Methylthioadenosine Nucleosidase and Human Methylthioadenosine Phosphorylase
  le: Harijan, Rajesh K., et al.
  Foilsithe: (2019)