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Repression of SRF target genes is critical for Myc-dependent apoptosis of epithelial cells
Oncogenic levels of Myc expression sensitize cells to multiple apoptotic stimuli, and this protects long-lived organisms from cancer development. How cells discriminate physiological from supraphysiological levels of Myc is largely unknown. Here, we show that induction of apoptosis by Myc in breast...
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| 出版年: | EMBO J |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BlackWell Publishing Ltd
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4474530/ https://ncbi.nlm.nih.gov/pubmed/25896507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490467 |
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