Repression of SRF target genes is critical for Myc-dependent apoptosis of epithelial cells

Oncogenic levels of Myc expression sensitize cells to multiple apoptotic stimuli, and this protects long-lived organisms from cancer development. How cells discriminate physiological from supraphysiological levels of Myc is largely unknown. Here, we show that induction of apoptosis by Myc in breast...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Wiese, Katrin E, Haikala, Heidi M, von Eyss, Björn, Wolf, Elmar, Esnault, Cyril, Rosenwald, Andreas, Treisman, Richard, Klefström, Juha, Eilers, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2015
Soggetti:
Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474530/
https://ncbi.nlm.nih.gov/pubmed/25896507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490467
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi