Aryl hydantoin Ro 13-3978, a broad-spectrum antischistosomal

OBJECTIVES: Praziquantel is the only drug available for the treatment of schistosomiasis and the state of the exhausted drug discovery pipeline is alarming. We restarted investigations on the abandoned antischistosomal Ro 13-3978, an aryl hydantoin discovered in the early 1980s by Hoffmann La-Roche....

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Bibliografiske detaljer
Udgivet i:J Antimicrob Chemother
Main Authors: Keiser, Jennifer, Panic, Gordana, Vargas, Mireille, Wang, Chunkai, Dong, Yuxiang, Gautam, Nagsen, Vennerstrom, Jonathan L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462663/
https://ncbi.nlm.nih.gov/pubmed/25691324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkv016
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