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Immunohistochemical Investigations of Treatment with Ro 13-3978, Praziquantel, Oxamniquine, and Mefloquine in Schistosoma mansoni-Infected Mice

To date, there is only one drug in use, praziquantel, to treat more than 250 million people afflicted with schistosomiasis, a debilitating parasitic disease. The aryl hydantoin Ro 13-3978 is a promising drug candidate with in vivo activity superior to that of praziquantel against both adult and juve...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Panic, Gordana, Ruf, Marie-Thérèse, Keiser, Jennifer
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700362/
https://ncbi.nlm.nih.gov/pubmed/28971860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01142-17
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